| INR | Clinical state |
|---|---|
| 2.0 – 2.5 | DVT prophylaxis |
| 2.0 – 3.0 | Treatment of DVT/PE Systemic embolus Atrial fibrillation TIAs LV mural thrombus Mitral valve repair |
| 2.5 – 3.5 | Tissue heart valves Mechanical prosthetic heart valves implanted after 1990 Recurrent DVT/PE |
| 3.0 – 3.5 | DVT/PE with lupus anticoagulant (a lower range may be sufficient) Mechanical prosthetic heart valves implanted before 1990 |